Kircher Lab website

CADD-SV – a framework to score the effect of structural variants

R Shiny website of the Saturation Mutagenesis manuscript

With this snakemake pipeline you can process your MPRA sequencing data (assignment and count). It is the standard MPRA pipeline of the IGVF consortium and a further development of MPRAflow.

With this workflow you can use the output of MPRAsnakeflow (reporter experiment barcode file) together with the MPRA library sequence design file to quantify the MPRA reporter expression. It can quantify variants as well as elements. using BCalm.

Library to analyse, filter and plot MPRA count data.

Basic scripts for creating an oligo design file