diff --git a/packages/smithy-http/.changes/next-release/smithy-http-bugfix-4d75836f71714fef8792632f0de556de.json b/packages/smithy-http/.changes/next-release/smithy-http-bugfix-4d75836f71714fef8792632f0de556de.json
new file mode 100644
index 000000000..950c4ab6e
--- /dev/null
+++ b/packages/smithy-http/.changes/next-release/smithy-http-bugfix-4d75836f71714fef8792632f0de556de.json
@@ -0,0 +1,4 @@
+{
+  "type": "bugfix",
+  "description": "Fixed `AIOHTTPClient` sending omitted request payloads with chunked transfer encoding."
+}
diff --git a/packages/smithy-http/src/smithy_http/aio/aiohttp.py b/packages/smithy-http/src/smithy_http/aio/aiohttp.py
index 5a330931d..c5f08a1b4 100644
--- a/packages/smithy-http/src/smithy_http/aio/aiohttp.py
+++ b/packages/smithy-http/src/smithy_http/aio/aiohttp.py
@@ -90,8 +90,13 @@ async def send(
             chain.from_iterable(fld.as_tuples() for fld in request.fields)
         )
 
-        body: StreamingBlob = request.body
-        if not isinstance(body, AsyncBytesReader):
+        body: StreamingBlob | None = request.body
+        if (
+            "content-length" not in request.fields
+            and "transfer-encoding" not in request.fields
+        ):
+            body = await self._prepare_body(body)
+        elif not isinstance(body, AsyncBytesReader):
             body = AsyncBytesReader(body)
 
         # The typing on `params` is incorrect, it'll happily accept a mapping whose
@@ -106,6 +111,19 @@ async def send(
         ) as resp:
             return await self._marshal_response(resp)
 
+    async def _prepare_body(self, body: StreamingBlob) -> AsyncBytesReader | None:
+        """Convert a body for aiohttp, omitting seekable bodies with no data."""
+        if not isinstance(body, AsyncBytesReader):
+            body = AsyncBytesReader(body)
+
+        if not body.seekable():
+            return body
+
+        position = await body.seek(0, 1)
+        end = await body.seek(0, 2)
+        await body.seek(position)
+        return None if position == end else body
+
     def _serialize_uri_without_query(self, uri: URI) -> yarl.URL:
         """Serialize all parts of the URI up to and including the path."""
         return yarl.URL.build(
diff --git a/packages/smithy-http/tests/unit/aio/test_aiohttp.py b/packages/smithy-http/tests/unit/aio/test_aiohttp.py
new file mode 100644
index 000000000..4f4548faf
--- /dev/null
+++ b/packages/smithy-http/tests/unit/aio/test_aiohttp.py
@@ -0,0 +1,80 @@
+#  Copyright Amazon.com, Inc. or its affiliates. All Rights Reserved.
+#  SPDX-License-Identifier: Apache-2.0
+#  pyright: reportPrivateUsage=false
+from collections.abc import AsyncIterator
+from typing import Any, cast
+from unittest.mock import AsyncMock, MagicMock
+
+from smithy_core import URI
+from smithy_core.aio.types import AsyncBytesReader
+from smithy_http import Field, Fields
+from smithy_http.aio import HTTPRequest
+from smithy_http.aio.aiohttp import AIOHTTPClient
+
+
+def _create_client() -> tuple[AIOHTTPClient, MagicMock]:
+    response = MagicMock(status=200, headers={}, reason="OK")
+    response.read = AsyncMock(return_value=b"")
+
+    session = MagicMock()
+    session.request.return_value.__aenter__ = AsyncMock(return_value=response)
+    session.request.return_value.__aexit__ = AsyncMock(return_value=None)
+    return AIOHTTPClient(_session=cast(Any, session)), session
+
+
+async def test_send_omits_empty_async_reader_body() -> None:
+    client, session = _create_client()
+    request = HTTPRequest(
+        method="GET",
+        destination=URI(scheme="https", host="example.com", path="/"),
+        body=AsyncBytesReader(b""),
+        fields=Fields(),
+    )
+
+    await client.send(request)
+
+    assert session.request.call_args.kwargs["data"] is None
+
+
+async def test_send_preserves_explicitly_framed_empty_body() -> None:
+    client, session = _create_client()
+    body = AsyncBytesReader(b"")
+    request = HTTPRequest(
+        method="GET",
+        destination=URI(scheme="https", host="example.com", path="/"),
+        body=body,
+        fields=Fields([Field(name="content-length", values=["0"])]),
+    )
+
+    await client.send(request)
+
+    assert session.request.call_args.kwargs["data"] is body
+
+
+async def test_prepare_body_preserves_nonempty_reader_position() -> None:
+    client, _ = _create_client()
+    body = AsyncBytesReader(b"request body")
+    assert await body.read(4) == b"requ"
+
+    prepared = await client._prepare_body(body)
+
+    assert prepared is body
+    assert await body.read() == b"est body"
+
+
+async def test_prepare_body_does_not_consume_nonseekable_body() -> None:
+    started = False
+
+    async def body() -> AsyncIterator[bytes]:
+        nonlocal started
+        started = True
+        yield b"request body"
+
+    client, _ = _create_client()
+    request_body = body()
+
+    prepared = await client._prepare_body(request_body)
+
+    assert started is False
+    assert prepared is not None
+    assert await prepared.read() == b"request body"