+
+
+ @if (selectedNodes().length) {
+
+ 1
+
+ {{ network.nodes.length }} logic nodes
+ Choose an input
+
+ check_circle
+
+ } @else {
+
+ Selected in diagram
+ {{ selectedName() || selectedStId() }}
+
+ {{ selectedStId() }} · {{ selectedNodes().length }} matching logic
+ {{ selectedNodes().length === 1 ? 'node' : 'nodes' }}
+
+
+
+ touch_app
+
+ }
+
+
+ Select a molecule on the pathway diagram
+
+ @if (selectedStId()) {
+ {{ selectedStId() }} is not represented in this DeltaSignal network. Choose another entity.
+ } @else {
+ The selected Reactome entity will be matched to its logic-network node or nodes.
+ }
+
+
+
+
+
+
+
+
+
+
+ × baseline
+
+
+
+
+
+
+
+
+
+
+ @if (service.perturbations().length) {
+
+ 2
+
+ @if (service.perturbations().length) {
+
+ }
+ Run prediction
+
+ @for (item of service.perturbations(); track item.reactomeId) {
+
+
+ } @else {
+
+
+ }
+
+ {{ item.name }}
+ {{ item.reactomeId }} · {{ item.activity }}× · {{ item.nodeUuids.length }} logic
+ {{ item.nodeUuids.length === 1 ? 'node' : 'nodes' }}
+
+
+ Add at least one perturbation to run a prediction.
+ } + + @if (service.error() && service.network()) { +
+
+
+
+ 3
+
+
+ Predicted response
+
+
+
+
+ {{ result.converged ? 'check_circle' : 'warning' }}
+ {{ result.converged ? 'Converged' : 'Did not converge' }}
+
+ {{ result.iterations }} iterations · {{ result.solve_time | number: '1.3-3' }} s
+
+ Lower than baseline
+
+ Higher than baseline
+
+ + Diagram colours show change from each node's own baseline. When several logic nodes map to one Reactome + entity, all values appear as a gradient. +
+ +
+
+ @if (service.entityRows().length > visibleRows().length) {
+
+ EntityActivityChangeInfluence
+
+ @for (row of visibleRows(); track row.uuid) {
+
+
+ {{ row.name }}
+ {{ row.reactomeId }}
+
+ {{ row.activity | number: '1.1-1' }}×
+
+ {{ row.change > 0 ? '+' : '' }}{{ row.change | number: '1.1-1' }}
+
+ {{ row.influence | number: '1.2-2' }}
+
+ }
+ + Showing the 40 largest predicted changes across {{ service.entityRows().length }} Reactome entities. +
+ } +