diff --git a/.changelog/5441.fixed b/.changelog/5441.fixed
new file mode 100644
index 0000000000..ee10a97e2c
--- /dev/null
+++ b/.changelog/5441.fixed
@@ -0,0 +1 @@
+`opentelemetry-sdk`: fix `TypeError` when instantiating a `_BaseConfigurator` subclass whose `__init__` takes arguments
diff --git a/opentelemetry-sdk/src/opentelemetry/sdk/_configuration/__init__.py b/opentelemetry-sdk/src/opentelemetry/sdk/_configuration/__init__.py
index 128c1e22fe..12912a6d04 100644
--- a/opentelemetry-sdk/src/opentelemetry/sdk/_configuration/__init__.py
+++ b/opentelemetry-sdk/src/opentelemetry/sdk/_configuration/__init__.py
@@ -681,7 +681,7 @@ class _BaseConfigurator(ABC):
 
     def __new__(cls, *args, **kwargs):
         if cls._instance is None:
-            cls._instance = object.__new__(cls, *args, **kwargs)
+            cls._instance = object.__new__(cls)
 
         return cls._instance
 
diff --git a/opentelemetry-sdk/tests/test_configurator.py b/opentelemetry-sdk/tests/test_configurator.py
index 694ed3e9e7..ea922049e6 100644
--- a/opentelemetry-sdk/tests/test_configurator.py
+++ b/opentelemetry-sdk/tests/test_configurator.py
@@ -1487,6 +1487,21 @@ def test_custom_configurator(self, mock_init_comp):
         }
         mock_init_comp.assert_called_once_with(**kwargs)
 
+    def test_custom_configurator_with_init_args(self):
+        class ConfiguratorWithArgs(_OTelSDKConfigurator):
+            def __init__(self, name, strict=False):
+                super().__init__()
+                self.name = name
+                self.strict = strict
+
+            def _configure(self, **kwargs):
+                pass
+
+        configurator = ConfiguratorWithArgs("TEST_NAME", strict=True)
+        self.assertEqual(configurator.name, "TEST_NAME")
+        self.assertTrue(configurator.strict)
+        self.assertIs(configurator, ConfiguratorWithArgs("TEST_NAME"))
+
 
 # Any test that calls _init_logging with setup_logging_handler=True
 # should call _init_logging within this context manager, to