diff --git a/python/pyarrow/array.pxi b/python/pyarrow/array.pxi
index e090b1d0b3d..ddd97dcdd7f 100644
--- a/python/pyarrow/array.pxi
+++ b/python/pyarrow/array.pxi
@@ -5384,7 +5384,8 @@ cdef object get_values(object obj, bint* is_pandas_object):
         is_pandas_object[0] = False
     else:
         result = pandas_api.get_values(pandas_api.series(obj, copy=False))
-        is_pandas_object[0] = False
+        # pandas ExtensionArrays (e.g. pd.array(...)) get pandas semantics
+        is_pandas_object[0] = pandas_api.is_extension_array_dtype(obj)
 
     return result
 
diff --git a/python/pyarrow/tests/test_array.py b/python/pyarrow/tests/test_array.py
index 63c0eb0bea4..8d442eae762 100644
--- a/python/pyarrow/tests/test_array.py
+++ b/python/pyarrow/tests/test_array.py
@@ -2631,6 +2631,17 @@ def test_pandas_null_sentinels_index():
     assert result.equals(expected)
 
 
+@pytest.mark.pandas
+def test_pandas_null_sentinels_extension_array():
+    # GH-35721 - pandas ExtensionArrays should use "from_pandas" semantics
+    import pandas as pd
+    arr = pd.array([1.2, np.nan], dtype=float)
+    result = pa.array(arr)
+    expected = pa.array([1.2, np.nan], from_pandas=True)
+    assert result.equals(expected)
+    assert result.null_count == 1
+
+
 @pytest.mark.numpy
 def test_array_roundtrip_from_numpy_datetimeD():
     arr = np.array([None, datetime.date(2017, 4, 4)], dtype='datetime64[D]')